Genetic Differences between Two Strains of Xylella fastidiosa Revealed by Suppression Subtractive Hybridization

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Genetic differences between two strains of Xylella fastidiosa revealed by suppression subtractive hybridization.

Suppression subtractive hybridization was used to rapidly identify 18 gene differences between a citrus variegated chlorosis (CVC) strain and a Pierce's disease of grape (PD) strain of Xylella fastidiosa. The results were validated as being highly representative of actual differences by comparison of the completely sequenced genome of a CVC strain with that of a PD strain.

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Suppression subtractive hybridization.

Suppression subtractive hybridization (SSH) is a widely used method for separating DNA molecules that distinguish two closely related DNA samples. Two of the main SSH applications are cDNA subtraction and genomic DNA subtraction. In fact, SSH is one of the most powerful and popular methods for generating subtracted cDNA or genomic DNA libraries. The SSH method is based on a suppression PCR effe...

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Transposon Tn1721 distribution among strains of Xylella fastidiosa.

Transposons are mobile genetic elements found within the genomes of various organisms including bacteria, fungi, plants and animals. Fragments of the transposon Tn1721 were found included in the genome of Xylella fastidiosa strain 9a5c. Regions from such fragments were PCR-amplified using specially designed primers (TNP(1) and TNP(2)). In order to detect insertions of the Tn1721 element, both p...

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Interaction between Xylella Fastidiosa and Curtobacterium Flaccumfaciens

Xylella fastidiosa (Xf) is a fastidious gram-negative, xylem-limited bacterium that causes diseases in many crops of economic importance, such as grape (Pierce’s disease), almond, peach, coffee, plum and citrus. Xf can infect all known Citrus sinensis cultivars and causes Citrus variegated chlorosis (CVC). One major endophyte isolated from CVC-asymptomatic plants is the bacterium Curtobacterium...

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Differentially Expressed Genes of Virulent and Nonvirulent Entamoeba histolytica Strains Identified by Suppression Subtractive Hybridization

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 2003

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.69.2.1315-1319.2003